Searchable abstracts of presentations at key conferences in endocrinology

ea0020p449 | Obesity and Metabolism | ECE2009

Metabolic syndrome highly correlates to non toxic multinodular goiter progression: iperinsulinism a way to growth

Citarrella Roberto , Chiofalo Francesco , Vetro Calogero , Lo Coco Alessio , Puleo Luciana

Background: Insulin-resistance phenomenon is a key factor in the pathogenesis of Metabolic Syndrome (MS). Several reports focus on the identification of a role of Insulin to trigger thyrocytes proliferation in vitro. Thyroid IRS-1 mRNA expression increased progressively during goitrogenesis in vivo. In order to individuate the impact of clinical and biochemical markers of MS on the growth-score of non toxic multinodular goiter (MNG) we evaluated a population of 6...